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Search Results for " chk1 in 2 "

5

Compounds

Cat No. Product Name Synonyms Targets
T10790 CHK1-IN-2 Chk
CHK1-IN-2 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 6 nM).
T3824 Jaceosidin Apoptosis , BCL , COX , UGT
Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...
T9666 GDC-0425
GDC-0425 (RG-7602) is an orally administered, selective small molecule inhibitor targeting checkpoint kinase 1 (ChK1), utilized in research focused on various malignancies [1] [2].
T36704 CCT241533 dihydrochloride CCT 241533 dihydrochloride
Potent Chk2 inhibitor (IC50 = 3 nM). Shows >63-fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. Inhibits Chk2 activation in response to etoposide-induced DNA damage in HT29 cells. Blocks ionizing radi...
T83740 Ziptide TFA
Ziptide, a peptide substrate, is recognized by several serine/threonine protein kinases, such as MAPK activated protein kinase 2 (MAPKAPK2), MAPKAPK3, MAPKAPK5, checkpoint kinase 1 (Chk1), AMP-activated protein kinase (A...
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